目的探讨9号染色体臂间倒位的遗传效应。方法常规技术方法制备外周血淋巴细胞染色体,G显带进行分析。结果2053例患者中检出9号染色体臂间倒位23例,其中15例为不良孕史及流产患者,4例为不孕不育,1例为原发性闭经,3例为合并智力低下等。结论9号染色体臂间倒位有一定的遗传效应,对该携带者应做产前诊断。 Objective To investigate the genetic effect of internodal inversion on chromosome 9. Methods Chromosomes of peripheral blood lymphocytes were prepared by routine techniques and analyzed by G banding. Results Twenty-three of the 2053 patients were detected with inversions on chromosome 9, 15 of whom had poor pregnancy history and abortion, 4 were infertile, 1 had primary amenorrhea, 3 had combined mental retardation Wait. Conclusion There is a certain genetic effect on the inversion of arm 9 on chromosome 9, and prenatal diagnosis should be done for this carrier.