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目的探讨妊娠晚期胎儿MCA血流参数与胎儿溶血性贫血的关系。方法采用前瞻性、小样本、随机对照研究方法,将患者分为母婴ABO血型不合组、正常对照组,进行胎儿MCA血流参数检测,测得收缩期峰值流速Vs,舒张期峰值流速Vd,搏动指数PI和阻力指数RI。结果血型不合组胎儿MCA的Vs、Vd高于正常对照组,差异有统计学意义(P<0.05);血型不合组与正常对照组胎儿MCA的PI、RI相比较,差异无统计学意义(P>0.05)。结论胎儿MCA血流参数测定对于预测胎儿宫内溶血性贫血有一定意义。
Objective To investigate the relationship between fetus MCA flow parameters and fetal hemolytic anemia in late pregnancy. Methods Using prospective, small sample and randomized controlled study, the patients were divided into maternal and child ABO incompatible group and normal control group. Fetal MCA blood flow parameters were measured. Peak systolic velocity Vs, diastolic peak velocity Vd, Pulsatile index PI and resistance index RI. Results The Vs and Vd of fetus with abnormal blood group were significantly higher than those of normal control group (P <0.05). There was no significant difference in PI and RI of fetus with abnormal blood group (P > 0.05). Conclusion Determination of fetal MCA blood flow parameters for the prediction of intrauterine hemolytic anemia has some significance.