Ti-Mo alloys with various Mo contents from 6wt%to 14wt%were processed by spark plasma sintering based on elemental pow-ders. The influence of sintering temperature and Mo content on the microstructure and mechanical properties of the resulting alloys were in-vestigated. For each Mo concentration, the optimum sintering temperature was determined, resulting in a fully dense and uniform micro-structure of the alloy. The optimized sintering temperature gradually increases in the range of 1100-1300°C with the increase in Mo content. The microstructure of the Ti-(6-12)Mo alloy consists of acicularαphase surrounded by equiaxed grains ofβphase, while the Ti-14Mo al-loy only contains singleβphase. A small amount of fineαlath precipitated fromβphase contributes to the improvement in strength and hardness of the alloys. Under the sintering condition at 1250°C, the Ti-12Mo alloy is found to possess superior mechanical properties with the Vickers hardness of Hv 472, the compressive yield strength of 2182 MPa, the compression rate of 32.7%, and the elastic modulus of 72.1 GPa. These results demonstrate that Ti-Mo alloys fabricated via spark plasma sintering are indeed a perspective candidate alloy for dental applications.