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研究了用益气健脾、滋补肝肾的补益中药复方，从调动机体自身的抗病毒能力入手，对乙肝患者血清 ＨＢＶ－Ｍ作用的影响。临床观察治疗组 ４０例，ＨＢＶ－Ｍ阴转率分别为 ＨＢｓＡｇ ４２．５％、ＨＢｅＡｇ ８１．３％，抗－ＨＢｅ ４６．７％，抗－ＨＢｃ ２５．６％；ＡＬＴ复常率 ８６.８％；肝大回缩率 ６３.３％；症状改善显效率８７．５％。除抗－ＨＢｃ外，其余各项均显著高于对照组（Ｐ<０．０５～０．０１）。提示用益气扶正治则，补益中药方剂治疗乙肝患者及ＨＢｓＡｇ携带者，是使ＨＢＶ－Ｍ阴转的另一途径。
To study the effect of replenishing qi and spleen and nourishing the liver and kidney tonic of traditional Chinese medicine, and to investigate the effect of HBV-M on serum HBV-M in patients with hepatitis B. In the clinical observation and treatment group of 40 patients, the negative conversion rate of HBV-M was 42.5% for HBsAg, 81.3% for HBeAg, 46.7% for anti-HBe, 25.6% for anti-HBc, and 86.8 for ALT. %; liver retraction rate was 63.3%; symptom improvement rate was 87.5%. Except for anti-HBc, all other items were significantly higher than the control group (P<0.05-0.01). It is suggested that the treatment of HBV-M negative transformation is to use qi to support the rule, and tonic prescription to treat hepatitis B patients and HBsAg carriers.