论文部分内容阅读
目的通过检测乙肝血清学指标阳性的产妇乳汁中乙肝两对半及外周血HBV-DNA定量,以探讨两者之间的关系及其对于母乳喂养的影响。方法对42例血清乙肝指标阳性的产妇,应用酶联免疫吸附法和荧光定量法检测乳汁中乙肝两对半及血HBV-DNA,42例血清乙肝指标阴性产妇作为对照组。结果 42例HBV携带孕妇产后乳汁乙肝两对半HbsAg检出率为33.3%。42例HBV携带孕妇HBV-DNA阳性率为28.57%。对照组乳汁HbsAg检出率为0,HBV-DNA阳性率为0。结论乙肝小三阳或仅HbsAg阳性的孕妇乳汁乙肝病毒检出率低,母乳喂养相对安全,并且其乳汁的传染性明显低于乙肝大三阳孕妇。乳汁乙肝两对半全阴且血清HBV-DNA处于正常范围的产妇提倡母乳喂养。
Objective To determine the relationship between HBV-DNA in two and a half of hepatitis B and HBV-DNA in peripheral blood of maternal milk with HBV seropositivity, so as to explore the relationship between the two and its impact on breastfeeding. Methods 42 pregnant women with positive serum HBV were detected by enzyme-linked immunosorbent assay (ELISA) and fluorescent quantitation method. HBV-DNA in serum was detected by two pairs of hemoglobin and HBV-DNA in serum and 42 negative pregnant women with serum HBV were used as control group. Results The positive rate of HBsAg in 42 HBV-infected pregnant women with postpartum breast milk was 33.3%. The positive rate of HBV-DNA in 42 HBV carriers was 28.57%. The control group milk HbsAg detection rate was 0, HBV-DNA positive rate was 0. Conclusion The detection rate of hepatitis B virus in breast milk of HBsAg-positive or HBsAg-positive pregnant women is relatively low, breastfeeding is relatively safe, and the infectivity of breast milk is obviously lower than HBsAg positive pregnant women. Breast milk Two pairs of semi-overcast and serum HBV-DNA in the normal range of mothers to promote breastfeeding.