为了探讨毗喹酮治疗日本棘隙吸虫病的疗效,对50例粪检阳性患者进行了观察。50例中男34例,女16例;成人6例,儿童44例;年龄为4～59岁。采用吡喹酮2～20mg/kg半空腹顿服。治毕7～10天连续3次集卵粪检的虫卵阴转率为94.9%(39/39)。治后出现轻微的头昏、头痛、乏力、恶心及荨麻疹等,一般无需特殊处理。治疗前后血、尿及肝功能等检查,除1例治后 SGPT 轻度升高外,未见明显异常。国内外尚未见吡喹 In order to investigate the efficacy of praziquantel in the treatment of Japanese echinococcosis, 50 cases of stool positive patients were observed. 50 cases of 34 males and 16 females; 6 adults, 44 children; aged 4 to 59 years. Praziquantel 2 ~ 20mg / kg half fasting Dayton clothing. After 7 to 10 days of treatment, ovic ovulation rate of the oviduct test was 94.9% (39/39). After treatment, mild dizziness, headache, fatigue, nausea and hives, etc., generally do not need special treatment. Before and after treatment of blood, urine and liver function tests, in addition to a case of SGPT mildly elevated, no significant abnormalities. No domestic and foreign praziquan