药物性肝损伤是指在治疗过程中由于药物的毒性损害或过敏反应所致的肝脏疾病。药物性肝损伤是常见肝脏疾病之一,多数表现为黄疸、转氨酶升高等,可伴有发热和皮疹,病程常可逆转,占黄疸和急性肝炎住院患者的2%~5%,非病毒性肝炎的20%~50%,急性肝功能衰竭的30%~40%,它还是不明原因肝损伤的常见原因,特别是50岁以上的患者,并且是引起暴发性肝衰竭的重要病因之一。目前 Drug-induced liver injury refers to liver disease caused by the toxicity of drugs or allergic reactions during the course of treatment. Drug-induced liver injury is one of the common liver diseases, the majority of manifestations of jaundice, elevated transaminases, may be associated with fever and rash, the course can be reversed, accounting for 2% to 5% of hospitalized patients with jaundice and acute hepatitis, non-viral hepatitis Of 20% to 50%, acute liver failure 30% to 40%, it is also a common cause of unexplained liver damage, especially in patients over the age of 50, and is one of the important causes of fulminant hepatic failure. Currently