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妊娠高血压综合征(Pregnancy-indused hypertension,PIH)是指妊娠20周后发生的高血压、蛋白尿、水肿症候群,严重威胁母、婴健康,其病因及发病机理尚无定论。目前对妊娠高血压综合征的免疫发病机理的研究主要包括HLA-DRB1、Th1细胞与Th2细胞的比例变化、蜕膜免疫细胞因子的变化等方面。
Pregnancy-indused hypertension (PIH) refers to hypertension, proteinuria and edema syndrome occurring after 20 weeks gestation. It is a serious threat to the health of infants and infants. The etiology and pathogenesis of PIH are not conclusive. At present, the study on the pathogenesis of pregnancy-induced hypertension mainly includes the changes of the proportion of HLA-DRB1, Th1 cells and Th2 cells and the changes of decidual immune cytokines.