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1.β细胞中胰岛素的前体是什么? 答:胰岛素来自前体分子——胰岛素原,后者在内质网合成。未明确肯定究在何处胰岛素原分子的C肽链裂解出去而产生胰岛素,但似在高尔基氏器。 2.胰岛素的储存形式是什么? 答:胰岛素分子以锌胰岛素复合物形式储于β颗粒。锌胰岛素复合物具晶体结构。
1. What are the precursors of insulin in beta cells? A: Insulin comes from the precursor molecule, proinsulin, which is synthesized in the endoplasmic reticulum. It is not clearly certain where the C-peptide of the proinsulin molecule is cleaved to produce insulin, but appears to be in the Gallbladder. 2. What is the storage form of insulin? A: Insulin molecules are stored as beta-insulin in the form of zinc-insulin complex. The zinc insulin complex has a crystal structure.