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目的：探讨肝硬变患者血清胃动素（ Ｍ Ｔ Ｌ），肽 Ｙ Ｙ（ Ｐ Ｙ Ｙ）， Ｉｇ Ｇ 和铁蛋白（ Ｆ Ｒ Ｔ）在肝硬变时的变化及其临床意义． 方法：临床确诊的肝硬变患者３５（男２８，女 ７）例，平均年龄（４２±７）岁，其中乙型肝炎后（ Ｈ Ｂｓ Ａｇ 阳性）３１ 例，酒精性 １例和原因不明３ 例． 伴消化道出血１９ 例，伴腹水２７ 例，伴肝性脑病９ 例和肝肾综合征４ 例．按肝功能级别（ Ｃｈｉｌｄ 分级）分为 Ａ 级１３ 例， Ｂ级１９ 例和 Ｃ级３ 例． 健康对照３２（男２４，女）８ 例，平均年龄（４１±９）岁． Ｍ Ｔ Ｌ， Ｐ Ｙ Ｙ， Ｉｇ Ｇ 和 Ｆ Ｒ Ｔ用放射免疫法测定． 结果：与对照比较，肝硬变患者血清 Ｍ Ｔ Ｌ （２０７±９８） ｎｇ／ Ｌ ｖｓ （３ １２６±１００） ｎｇ／ Ｌ，（ Ｐ＜ ０．０１）， Ｐ Ｙ Ｙ （１．１±０６） ｐｍ ｏｌ／ Ｌ ｖｓ （１．６±０．８） ｐｍ ｏｌ／ Ｌ，（ Ｐ＜ ０． ０５） 和 Ｉｇ Ｇ（１３１±７０） ｇ／ Ｌ ｖｓ （２３．６±１０．２）ｇ／ Ｌ，（ Ｐ＜ ０．０１）明显升高，而 Ｆ Ｒ Ｔ （１８７±８５） μｇ／ Ｌ ｖｓ （９８±４１） μｇ／ Ｌ，（ Ｐ＜ ０．０１）明显升高，血清 Ｍ Ｔ Ｌ升高与 Ｐ Ｙ Ｙ 升高呈正相关 ?
Objective: To investigate the changes of serum motilin (PTH), peptide YY (P Y), Ig G and ferritin (F R T) in patients with liver cirrhosis and their clinical significance. Methods: 35 (28 males and 7 females) with clinically diagnosed cirrhosis were enrolled in this study. The mean age was (42 ± 7) years. Among them, 31 were HbsAg-positive, 1 was alcoholic, and 3 example. 19 cases with gastrointestinal bleeding, 27 cases with ascites, 9 cases with hepatic encephalopathy and 4 cases with hepatorenal syndrome. According to the level of liver function (Child classification) was divided into A grade 13 cases, B grade 19 cases and C grade 3 cases. Health control 32 (M 24, F 8), mean age (41 ± 9) years old. M T L, P Y Y, Ig G and F R T were determined by radioimmunoassay. Results: Compared with the control group, the serum levels of M T L (207 ± 98) ng / L vs (31,66 ± 100) ng / L, P Y (1.1 ± 0) (P <0.05) and Ig G (131 ± 70) g / L vs (23.6 ± 10.2) g / L, (P <0.01), while F R T (187 ± 85) μg / L vs (98 ± 41) μg / L, High, serum M T L increased and P Y Y was positively correlated?