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目的:探讨足月新生儿脐静脉血肝功能指标与早期新生儿黄疸的关系。方法:选我院足月健康出生的新生儿120例作为研究对象,对这120例新生儿脐静脉血进行肝功能的测定,根据新生儿在两天内是否出现黄疸将其分为黄疸组与非黄疸组,每组各60例,对两组新生儿的脐血肝功能检测结果进行比较分析。将新生儿脐血中总胆红素、间接胆红素以及白蛋白的含量与早期新生儿出现黄疸的关系做一个分析。结果:黄疸组脐静脉血各项肝功能指标的数值都明显高于非黄疸组,P<0.05,其中的脐血总胆红素的量大于等于30umol/L、间接胆红素的量大于等于20umol/L,这表明着在2天内发生黄疸的可能性是非常高的,但是其中的脐血白蛋白值比较没有显著差异,也没有统计学意义。结论:足月新生儿脐血静脉肝功能指标水平能够用在预测早期新生儿是否出现黄疸上,脐静脉血中的肝功能指标总胆红素与间接胆红素与黄疸关系为正相关,但脐血白蛋白与其没有太大关系,无影响。
Objective: To investigate the relationship between neonatal umbilical venous blood and full-term neonatal jaundice. Methods: A total of 120 newborn infants born in term full-term in our hospital were enrolled in this study. The liver function of 120 neonates with umbilical venous blood was measured. According to whether newborns had jaundice within two days, they were divided into jaundice group and non-jaundice group Jaundice group, 60 cases in each group, comparative analysis of the results of cord blood liver function tests between two groups of newborns. The neonatal umbilical cord blood total bilirubin, indirect bilirubin and albumin content and early neonatal jaundice an analysis of the relationship. Results: The values of various indexes of liver function in umbilical cord blood of jaundice group were significantly higher than those of non-jaundice group (P <0.05), the amount of total bilirubin in umbilical cord blood was 30umol / L or more, the amount of indirect bilirubin was greater than or equal to 20umol / L, indicating that the likelihood of developing jaundice within 2 days is very high, but the values of umbilical serum albumin were not significantly different nor statistically significant. Conclusion: The index of liver function in full-term newborn can be used to predict the occurrence of jaundice in early neonates. The correlation between total bilirubin, indirect bilirubin and jaundice in umbilical venous blood is positive Umbilical serum albumin and its not too much, no effect.