目的观察雷贝拉唑治疗反流性食管炎的效果。方法将我院80例反流性食管炎患者随机分为治疗组及对照组,对照组患者服用西沙必利,治疗组患者在对照组基础上加服雷贝拉唑。结果经过治疗,治疗组的总有效率为90.8%,显著高于对照组的69.0%,差异有统计学意义(p<0.05)。治疗组3例出现腹泻、口干,约几天后症状消失;对照组有1例出现头晕,1例肝功能有轻微损害,但可坚持整个疗程药物治疗。结论采用雷贝拉唑治疗反流性食管炎,可有效对食管进行保护,最大限度减少返流的发生,减少胃酸对食管粘膜的损伤,从而促进粘膜尽快恢复,达到缓解返流症状,且毒副作用少,安全性可靠,值得推广应用。 Objective To observe the effect of rabeprazole on reflux esophagitis. Methods 80 patients with reflux esophagitis in our hospital were randomly divided into treatment group and control group. Patients in control group were given cisapride. Patients in treatment group were given rabeprazole on the basis of control group. Results After treatment, the total effective rate of the treatment group was 90.8%, which was significantly higher than that of the control group (69.0%), the difference was statistically significant (p <0.05). In the treatment group, 3 cases had diarrhea and dry mouth, and the symptoms disappeared after about a few days. In the control group, 1 case had dizziness and 1 case had slight damage to liver function, but could insist on the whole course of drug treatment. Conclusion The use of rabeprazole in the treatment of reflux esophagitis can effectively protect the esophagus, minimize the incidence of reflux, reduce gastric acid damage to the esophageal mucosa, thereby promoting the mucosal recovery as soon as possible to alleviate the symptoms of reflux, and the toxicity Less side effects, safe and reliable, it is worth promoting application.