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目的:分析新疆地区近20年来胃癌流行病学特征,探讨其变化规律及发展趋势。方法:回顾性分析和比较1991年、2001年、2011年经新疆维吾自治区人民医院胃镜及病理学诊断确诊为胃癌的病例的一般资料、病理学及内镜下特点,包括性别、年龄、病理类型、发病部位。结果:1991年组:胃癌检出率为2.48%,中位年龄为54岁,男女之比为3.3:1.0,发病部位以胃窦部癌为主,占39.1%;2001年组:检出率为2.39%,中位年龄为61岁,男女之比为3.0:1.0,发病部位以胃体部癌为主,占42.1%;2011年组:检出率为1.48%,中位年龄为63岁,男女之比为3.9:1.0,发病部位以贲门胃底部为主,占34.8%。三组病理学类型均以腺癌为主,检出率有逐年升高趋势,但差异无统计学意义(P>0.05)。结论:(1)近20年来胃癌发病部位有上移现象,且胃癌检发病率有下降趋势;(2)男性胃癌患者发病率明显高于女性,且近20年来胃癌患者男女比例无明显改变;(3)近20年来胃癌发病中位年龄逐渐增高,且随着年龄的增长发病率逐渐升高,以中老年发病率最高;(4)癌患者病理类型仍以腺癌为主,且近20年来腺癌所占比例无明显变化。
OBJECTIVE: To analyze the epidemiological characteristics of gastric cancer in Xinjiang in the recent 20 years and to explore its changing rules and development trend. Methods: The general information, pathology and endoscopic features of gastric cancer diagnosed by gastroscopy and pathology diagnosed by People's Hospital of Xinjiang Uygur Autonomous Region in 1991, 2001 and 2011 were retrospectively analyzed and compared, including sex, age, pathology Type, the site of the disease. Results: In 1991, the detection rate of gastric cancer was 2.48%, the median age was 54 years old, the ratio of male to female was 3.3: 1.0, and the incidence of gastric cancer was 39.1%. In 2001, the detection rate Was 2.39%. The median age was 61 years. The ratio of male to female was 3.0: 1.0. The main part of the disease was gastric cancer, accounting for 42.1%. In 2011, the detection rate was 1.48% and the median age was 63 years , The ratio of men to women was 3.9: 1.0, the incidence of parts of the stomach mainly to the cardia, accounting for 34.8%. The pathological types of the three groups were mainly adenocarcinoma, and the detection rate increased year by year, but the difference was not statistically significant (P> 0.05). (2) The incidence of gastric cancer in men is significantly higher than that in women, and the proportion of male and female in gastric cancer has no obvious change in the past 20 years; (3) The median age of gastric cancer gradually increased in the recent 20 years, and the incidence increased gradually with the increase of age, with the highest incidence of middle-aged and elderly patients; (4) The pathological types of cancer patients were still mainly adenocarcinoma, and nearly 20 No significant change in the proportion of adenocarcinoma over the years.