We propose an image retrieval method based on interest image region by asymmetrical blocking.An image is segmented into the interest region and background region on a certain rule.For the interest image regions,the color histogram of the uneven blocks is extracted as the color characteristic.We also collect the mean and variance value of the Gabor filtering results of background blocks as texture features of the background image.Then,the images can be retrieved by synthesizing the image color and texture features.We test our approaches by analyzing the results of recall and precision indicators for the Corel image database.The experiment results show that the proposed method performs effectively and accurately,which is more effective to retrieve the distant-view images,and the achieved precision increases by about 10％ without loss of the retrieval call compared with some other traditional search methods.