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目的观察注射用低分子肝素治疗进展性脑梗死的疗效及该药对出凝血指标的影响。方法临床诊断进展性脑梗死患者应用注射用低分子肝素钙4 800U皮下注射,每12h1次连续使用1周,进行临床观察并与对照组比较,同时观察治疗组在使用低分子肝素前后血小板及INR的变化。结果治疗组有效控制率均明显高于对照组(P<0.01),治疗组用药前后BPT、INR差异无统计学意义(P>0.05),未发现明显不良反应。结论低分子肝素是治疗进展性脑梗死的一种安全、有效的药物。
Objective To observe the curative effect of injecting low molecular weight heparin on patients with progressive cerebral infarction and the effect of this medicine on coagulation index. Methods Clinical diagnosis of patients with progressive cerebral infarction with injection of low molecular weight heparin calcium 800U subcutaneous injection every 12h1 continuous use for 1 week, the clinical observation and compared with the control group, while observing the treatment group before and after the use of low molecular weight heparin platelet and INR The change. Results The effective control rate in the treatment group was significantly higher than that in the control group (P <0.01). There was no significant difference in BPT and INR before and after treatment in the treatment group (P> 0.05). No obvious adverse reactions were found. Conclusion Low molecular weight heparin is a safe and effective drug for the treatment of progressive cerebral infarction.