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目的探讨分析吸入用复方异丙托溴铵溶液(可必特)与布地奈德在反复呼吸道感染中的应用效果。方法 86例反复呼吸道感染患儿,随机分为观察组和对照组,各43例。观察组患儿给予可比特联合布地奈德治疗,对照组患儿单纯应用布地奈德治疗,比较两组患儿治疗效果和临床指标消失时间。结果观察组显效27例,有效15例,无效1例,总有效率为97.67%,对照组显效14例,有效19例,无效10例,总有效率为76.74%,观察组优于对照组(P<0.05)。观察组肺部啰音消失时间(4.57±1.39)d,喘憋缓解时间(2.23±1.20)d,咳嗽消失时间(6.03±1.88)d,平均住院时间(7.21±2.04)d;对照组肺部啰音消失时间(5.24±1.45)d,喘憋缓解时间(3.16±2.07)d,咳嗽消失时间(7.14±1.33)d,平均住院时间(8.36±1.98)d,观察组各项临床指标均优于对照组,比较差异有统计学意义(P<0.05)。结论可必特联合布地奈德治疗反复呼吸道感染效果显著,能明显改善患儿临床症状,病程缩短且未发现任何不良反应,值得临床推广应用。
Objective To investigate the effect of inhaled compound ipratropium bromide solution (may be special) and budesonide in recurrent respiratory tract infection. Methods Totally 86 children with recurrent respiratory tract infection were randomly divided into observation group and control group, with 43 cases in each group. Patients in the observation group received combination of budesonide and budesonide, while those in the control group received budesonide alone. The treatment effect and disappearance of clinical indexes in both groups were compared. Results The observation group was markedly effective in 27 cases, effective in 15 cases, ineffective in 1 case, the total effective rate was 97.67%, the control group markedly effective in 14 cases, effective in 19 cases, ineffective in 10 cases, the total effective rate was 76.74% P <0.05). The pulmonary rales disappeared in the observation group (4.57 ± 1.39 d), the time to relieve asthma (2.23 ± 1.20 d), the time to cough disappearance (6.03 ± 1.88 d) and the average length of hospital stay (7.21 ± 2.04 d) The duration of disappearance of rales (5.24 ± 1.45) d, the time of relieving asthma (3.16 ± 2.07) d, the time of disappearance of cough (7.14 ± 1.33) days and the average length of hospital stay (8.36 ± 1.98) days were all significantly improved In the control group, the difference was statistically significant (P <0.05). Conclusion Combination of budesonide and budesonide is effective in treating recurrent respiratory tract infections, and can significantly improve the clinical symptoms, shorten the course of the disease and found no adverse reactions, which is worthy of clinical application.