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[目的]探讨直肠癌肿瘤的ADC值与直肠癌临床病理因素的相关性。[方法]选取2013年10月至2014年10月根治术的直肠癌初治患者360例,术前均行MRI平扫及DWI扫描,测量直肠癌肿瘤的ADC值。分析ADC值与各分组因素的相关性。[结果 ]单因素分析显示不同病理类型、不同分化程度的肿瘤ADC值差异均有统计学意义(P均<0.001),而不同大体分型、术后T分期、淋巴结转移及MRF浸润的肿瘤ADC值差异无统计学意义。多因素分析显示分化程度和T分期的交互作用对ADC值有显著性影响(P=0.045)。[结论]肿瘤ADC值与肿瘤的病理类型、分化程度及T分期的交互作用相关。
[Objective] To investigate the correlation between the ADC value of rectal cancer and the clinicopathological factors of rectal cancer. [Methods] A total of 360 patients with primary rectal cancer undergoing radical operation from October 2013 to October 2014 were enrolled in this study. The ADC value of rectal cancer was measured by MRI and DWI before operation. Analyze the correlation between ADC values and grouping factors. [Results] The univariate analysis showed that the ADC values of different pathological types and different degrees of differentiation were statistically different (all P <0.001), while those with different general classification, postoperative T stage, lymph node metastasis and MRF infiltration No significant difference in value. Multivariate analysis showed that the interaction between differentiation and T staging had a significant effect on ADC value (P = 0.045). [Conclusion] The ADC value of tumor correlated with the pathological type, differentiation degree and T stage of the tumor.