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目的探究补肾化痰助孕方联合达英-35治疗多囊卵巢综合征(PCOS)的临床效果。方法选取2014年3月-2015年8月该院收治的PCOS患者120例为研究对象。按照随机数字表法将120例患者分为两组,随机数字为奇数者为观察组,偶数者为对照组,每组患者60例。观察组采用补肾化痰助孕方联合达英-35治疗;对照组单纯采用达英-35治疗,两组均共治疗3个周期,治疗后观察并比较患者的月经恢复情况、治疗前后的血激素睾酮(T)、排卵率及黄体生成素/卵泡刺激素(LH/FSH)水平变化。结果 3个周期治疗后,观察组月经恢复人数(完全恢复+基本恢复)约占88.3%,对照组月经恢复人数约为75.0%,观察组月经完全恢复人数明显高于对照组,差异有统计学意义(χ~2=5.829,P=0.016);对照组排卵率明显低于观察组,差异有统计学意义(χ~2=12.150,P<0.001)。两组患者T值及LH/FSH值均明显降低,且观察组治疗效果明显优于对照组,差异有统计学意义(t=4.952,P<0.001;t=2.311,P=0.023)。结论补肾化痰助孕方联合达英-35对于PCOS患者的治疗效果高于单纯的西药治疗,促进卵泡的发育与成熟的同时还可诱发排卵,对于提升妊娠率非常有帮助,值得临床推广。
Objective To investigate the clinical effects of tonifying kidney and resolving phlegm-phlegm-assisted pregnancy combined with Da Ying-35 in the treatment of polycystic ovary syndrome (PCOS). Methods A total of 120 PCOS patients admitted to our hospital from March 2014 to August 2015 were selected as the study subjects. According to the random number table method, 120 patients were divided into two groups. The random number was odd number and the even number was the control group, with 60 patients in each group. The observation group was treated with tonifying the kidney and phlegm, and the pregnant women were treated with up to Ying-35. The control group was treated with up to Ying-35 only. Both groups were treated for 3 cycles. After the treatment, the menstrual recovery and the blood before and after treatment were observed and compared Hormone testosterone (T), ovulation rate and luteinizing hormone / follicle stimulating hormone (LH / FSH) levels. Results After three cycles of treatment, the number of menstrual recovery (complete recovery + basic recovery) in the observation group accounted for about 88.3%, and the number of menstruation recovered in the control group was 75.0%. The number of full recovery of menstruation in the observation group was significantly higher than that of the control group (Χ ~ 2 = 5.829, P = 0.016). The ovulation rate of the control group was significantly lower than that of the observation group (χ ~ 2 = 12.150, P <0.001). The values of T and LH / FSH in both groups were significantly lower than those in the control group (t = 4.952, P <0.001; t = 2.311, P = 0.023). Conclusion Bushenhuatan combined with Da-Ying-35 for patients with PCOS treatment is higher than the simple Western medicine treatment to promote follicular development and maturation can also induce ovulation, for the promotion of pregnancy rate is very helpful, worthy of clinical promotion.