输卵管积水及其治疗对胚胎种植影响的评价

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输卵管积水患者行体外受精-胚胎移植(IVF-ET)后妊娠率降低,积水对IVF的负面影响包括:1机械性冲刷;2对配子及胚胎的毒性作用;3子宫内膜容受性下降等。改善此类患者IVF结局的主要方法是阻断输卵管积水返流至宫腔;输卵管积水的处理方式应根据患者的临床症状、既往助孕结局而个体化地选择输卵管切除术、近端输卵管结扎术、输卵管造口术等。对输卵管病变较轻、功能尚可者应行输卵管造口术引流积水;对于重度积水或伴积脓、确无功能者可在IVF前切除患侧输卵管或行近端输卵管结扎术;Essure近端栓塞术对有手术禁忌证的IVF患者不失为一种选择,但有效性有待进一步观察;输卵管穿刺积水抽吸术可作为超促排卵过程新发积水的一种临时处理方式。输卵管积水最优化的治疗方案仍有待进一步评估。 The incidence of IVF in hydronephrosis patients was lower after IVF-ET. The negative effects of hydronephrosis on IVF included: 1 mechanical scouring; 2 toxic effects on gametes and embryos; 3 endometrial receptivity Drop and so on. The main way to improve the outcome of IVF in such patients is to block the return of hydronephrosis to the uterine cavity. The treatment of hydrosalpinx should be based on the patient’s clinical symptoms, past pregnancy outcomes and the individual selection of tubal resection, proximal fallopian tubes Ligation, tubal ostomy. For tubal lesions lighter, function should be OK tubal drainage of hydrothorax; for severe hydrocephalus or with empyema, indeed no function in patients with IVF before removal of tubal or proximal tubal ligation; Essure Proximal end-to-end embolization is an option for IVF patients with surgical contraindications, but its effectiveness needs to be further observed. Aspirotis hydrops aspiration treatment can be used as a temporary treatment for newly developed hydrosalpinx. Tubal hydrops optimal treatment options remain to be further evaluated.
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