目的 :观察奥曲肽对脑出血并发上消化道出血的疗效。方法 :78例脑出血病人随机分为第 1组 2 7例 ,第 2组 2 5例 ,第 3组 2 6例。全部病人按常规方案治疗脑出血。第 1组加用奥曲肽 (首剂0 .1mg ,iv ,继后 0 .3mg ,ivgtt ,qd) ,疗程 3d。第 2组加用法莫替丁 (40mg ,ivgtt ,qd) ,疗程 7d。第 3组不用奥曲肽或法莫替丁。观察上消化道出血和死亡的发生例数。结果 :第 1组的上消化道出血及死亡发生率显著低于第 3组 (7%和 7%vs 38%和31% ) ,P <0 .0 1。第 2组与第 3组的上消化道出血发生率 (12 %vs 38% ) ,P <0 .0 5。第 1组与第 2组出血率和死亡率 (7% ,7%vs 12 % ,8% ) ,P >0 .0 5。结论 :奥曲肽能较好地治疗脑出血并发上消化道出血 Objective: To observe the effect of octreotide on cerebral hemorrhage complicated by upper gastrointestinal bleeding. Methods: A total of 78 patients with intracerebral hemorrhage were randomly divided into the first group of 27 cases, the second group of 25 cases, the third group of 26 cases. All patients according to conventional treatment of cerebral hemorrhage. The first group plus octreotide (the first dose of 0. 1mg, iv, followed by 0.3mg, ivgtt, qd), course of treatment 3d. Group 2 plus famotidine (40mg, ivgtt, qd), treatment 7d. Group 3 did not use octreotide or famotidine. Observe the number of cases of upper gastrointestinal bleeding and death. Results: The incidence of upper gastrointestinal bleeding and death in group 1 was significantly lower than in group 3 (7% vs 7% vs 38% vs 31%), P <0.01. The incidence of upper gastrointestinal bleeding in Groups 2 and 3 (12% vs 38%), P <0.05. Bleeding and mortality in groups 1 and 2 (7%, 7% vs 12%, 8%), P> 0.05. Conclusion: Octreotide can treat cerebral hemorrhage complicated with upper gastrointestinal bleeding better