论文部分内容阅读
目的 探讨用预测可能发生心律失常的心电学指标QT间期离散度 (QTd)和P波离散度 (Pd)来研究皮肤黏膜淋巴结综合征 (MCLS)患儿发生心律失常的可能性。方法 MCLS患儿 6 2例 (13例伴有冠脉扩张 ) ,随机匹配 79例健康儿童为对照。采用广东中山SR - 10 0 0A心电综合自动分析仪描记 12导联同步体表心电图 (12ECG) ,选择波形清晰的 3个心动周期 ,在人工干预下自动测量窦性节律时心率 (HR)、QTmax、QTmin、Pmax、Pmin ,计算QTd及Pd ,连测 3次后取其平均值。结果 与对照组比较 ,MCLS组急性期心率增快 (P <0 0 1) ,QTmax、QTmin缩短 ,QTd增大 ,Pmax增加 ,Pmin缩短 ,Pd增大 ;恢复期QTd、Pmax、Pd延长 ,其差异均有显著性 (P <0 0 1或P <0 0 5 )。伴有冠脉扩张与不伴有冠脉扩张的MCLS患儿之间QTmax、QTmin、QTd、Pmax、Pmin、Pd差异无显著性 (P >0 0 5 )。结论 MCLS能引起QTd及Pd增加 ,有可能发生严重心律失常 ,临床上不容忽视
Objective To investigate the possibility of arrhythmia in children with cutaneous mucosal lymph node syndrome (MCLS) by predicting the QTd and P wave dispersion (QTd) and the P wave dispersion (Pd), which predict cardiac arrhythmia. Methods Sixty-two children with MCLS (13 patients with coronary artery dilatation) were randomly allocated to 79 matched healthy children. The heart rate (HR) of sinus rhythm was measured automatically with manual intervention after selecting the 12 ECGs of 12 lead ECG (ECG) by SR - 100A ECG analyzer. QTmax, QTmin, Pmax, Pmin, calculated QTd and Pd, even measured three times and then take the average. Results Compared with the control group, the heart rate of MCLS group in acute phase increased (P <0.01), QTmax and QTmin shortened, QTd increased, Pmax increased, Pmin shortened and Pd increased, while QTd, Pmax and Pd prolonged in recovery group The difference was significant (P <0.01 or P <0.05). There were no significant differences in QTmax, QTmin, QTd, Pmax, Pmin and Pd between MCLS children with coronary artery dilatation and coronary artery dilation (P> 0.05). Conclusion MCLS can cause QTd and Pd increase, it is possible to have serious arrhythmia, which can not be neglected clinically