简单氨基酸的亚氨酸酯衍生物可以方便地由腈、氨垫酸酯制备。我们曾研究了N-乙氧羰基亚甲基苯甲亚氨酸乙酯、N-乙氧羰基亚甲基乙亚氨酸乙酯和N-氰甲基苯甲亚氨酸乙酯(1)在相转移催化条件下的烷基化反应,合成了一系列碳链增长的氨基酸。结果表明,这一方法原料易得,操作简便,是合成α-氨基酸的另一条新路线。本文研究了陶-液相相转移催化条件下, Imino ester derivatives of simple amino acids can be conveniently prepared from nitrile, urethane. We have studied N-ethoxycarbonylmethylenebenzimidate, N-ethoxycarbonylmethyleneacetimidate and N-cyanomethylbenzimidate (1) A series of amino acids with increased carbon chain have been synthesized by alkylation under phase-transfer catalysis. The results show that this method is easy to obtain raw materials, easy to operate, is another new route for the synthesis of α-amino acids. This article studies the pottery-liquid phase transfer catalysis conditions,