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患者女,20岁,声音嘶哑并逐渐加重,出现睡眠时打鼾,偶感呼吸困难,时有憋醒1年余。曾多次在当地医院就诊,一直未能明确诊断。近2月来,患者上述症状加重而就诊于我院,经纤维喉镜及颈部CT检查后,拟诊为喉囊肿。于1999年11月9日在全麻下行气管切开、喉部肿物切除术。术中见大小约3cm国×5cm一肿物占据左侧声带、喉室(左声带)、喉前庭,肿物表面有光滑被膜,与周围组织无粘连,内有脂肪滴及皮脂样物。经病理学证实为(左声带)粘液样软骨肉瘤;免疫组化示:Viementin(++)、S—100(++)、AEl/AE3(-)、NES(+)。 讨论 粘液样软骨肉瘤罕见,其发生部位可在骨内,但在软组织中的发病率也较高。肿物外观大体呈灰白色、质软、有大量粘液;在光镜下肿瘤细胞体积小呈圆形或星状,胞
Female patient, 20 years old, hoarseness and gradually increased, there is snoring sleep, occasional dyspnea, when I wake up more than 1 year. Has repeatedly visited a local hospital, has not been able to confirm the diagnosis. The past two months, the patient’s symptoms worsened and treated in our hospital, the fiber laryngoscope and neck CT examination, the proposed diagnosis of laryngeal cyst. On November 9, 1999 under general anesthesia tracheotomy, laryngectomy. Surgery see the size of about 3cm country × 5cm a tumor occupies the left vocal cord, throat room (left vocal cord), throat vestibule, tumor surface smooth coating, no adhesions with the surrounding tissue, there are fat droplets and sebum samples. Pathologically confirmed as (left vocal cord) mucoid chondrosarcoma; immunohistochemistry showed: Viementin (++), S-100 (++), AEl / AE3 (-), NES (+). DISCUSSION Mucous chondrosarcoma is uncommon and its site of occurrence is within the bone, but the incidence in soft tissue is also high. Tumor appearance is generally pale, soft, with a large number of mucus; tumor cells in the light microscope small circular or star-shaped cells