酒精性肝病含以下系列肝损害：酒精性脂肪肝、酒精性肝炎及酒精性肝硬化。我们在整理古代文献、流行病学调查、临床观察等方面，都发现脾虚证在酒精性肝病的发病中占有突出地位，在此基础上采用周氏报道的造模方法［１］，给大鼠灌饮白酒造成酒精性肝损害动物模型，以观察酒精性肝损害与脾虚证的关系。 Alcoholic liver disease with the following series of liver damage: alcoholic fatty liver, alcoholic hepatitis and alcoholic cirrhosis. In sorting out the ancient literature, epidemiological investigation and clinical observation, we found that spleen deficiency syndrome plays a prominent role in the pathogenesis of alcoholic liver disease. On the basis of this, we used the modeling method reported by Zhou [1] Induction of alcoholic liver damage caused by drinking alcohol liquor animal model to observe the relationship between alcoholic liver damage and spleen deficiency syndrome.