An electrostrictive uniaxial ultrasonic levitation reaction system was designed to perform TiC synthesis reaction by suspending graphite powder in Al-3Ti melt and an Al-3Ti-0.15C grain refiner alloy was obtained. The results show that sound pressure node in which graphite suspends is formed in the melt between radiation block and reflecting board by ultrasonic and TiAl3 particles congregate around C powder. Meanwhile, due to ultrasonic cavitation, dissolved TiAl3 provides better surface condition for the synthesis reaction of TiC. The reaction route is that C and dissolved Ti react to form TiC. Ultrasonic cavitation has a thermal activation effect on TiC particles and Al-3Ti-0.15C refiner has excellent microstructural refining effect on α-Al.