论文部分内容阅读
1987年5月,在英国伦敦召开了第六届国际病毒性肝炎会议,兹将有关乙型肝炎病毒(HBV)分子生物学研究归纳如下: 一、基因功能区亚克隆的表达随着对HBV核苷酸序列的阐明,基因功能区的定位,又建立了Pre-S_1、Pre-S_2、S、C、X功能区的亚克隆及相应的体外表达系统,进行了疫苗与诊断试剂的研制,表达调节及致病机理的研究。意大利Levreo与法国Vitvitki等分别报告建立X亚克隆在哺乳动
In May 1987, the Sixth International Conference on Viral Hepatitis was held in London, England. The study on molecular biology of Hepatitis B virus (HBV) will be summarized as follows: First, the expression of subclone of gene function domain Nucleotide sequence and gene function region. The subclone of Pre-S_1, Pre-S_2, S, C and X functional regions and corresponding in vitro expression system were also established. The vaccine and diagnostic reagents were developed and expressed Regulation and pathogenesis of the study. Italy Levreo and France Vitvitki respectively reported the establishment of X subclones in mammals