论文部分内容阅读
(一)机体免疫状态的研究进展:HBV 感染的免疫反应至少涉及病毒及其在肝脏内繁殖所造成的三个抗原系统(HBsAg、HBcAg、HBeAg)。乙型肝炎患者肝细胞损害的发病机理,目前还是一个推测和假说的问题。现一般认为,发病机理与机体对HBsAg 免疫反应有关,而与HBV 本身对肝细胞致病变的直接作用关系甚微。Dudley 认为乙型肝炎的临床类型主要决定于机体细胞免疫功能是否低下而与病毒本身无关。当HBV 侵入健康者的肝细胞后,被HBV 致敏的T 淋巴细胞充分发挥其功能将
(A) the research progress of the immune status of the body: The immune response of HBV infection involves at least three antigens system (HBsAg, HBcAg, HBeAg) caused by the virus and its multiplication in the liver. The pathogenesis of hepatocellular damage in hepatitis B patients is still a matter of speculation and hypothesis. It is generally believed that the pathogenesis of the body and the immune response to HBsAg, but with HBV itself on the direct effect of liver cell disease has little to do. Dudley that the clinical type of hepatitis B mainly depends on whether the body’s cellular immune function is low and has nothing to do with the virus itself. When HBV invades healthy liver cells, T lymphocytes that are sensitized by HBV give full play to their function