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目的探讨胃癌伴呕血术前化疗栓塞的疗效观察,不良反应及对手术切除率的影响。方法胃癌伴呕血患者65例,分为化疗栓塞后手术组和单纯手术组。化疗栓塞后手术组30例,测量化疗栓塞后其大小、形态的变化,肿瘤坏死的程度及不良反应,7~15d后行手术切除,统计手术时间,术中出血量,手术切除率及生存时间,并与单纯手术组35例进行比较。结果①化疗栓塞可使呕血消失、肿瘤发生一定程度的坏死,并使病变范围有所缩小,不良反应轻微。②化疗栓塞后再行手术切除,不仅可提高手术切除率,还可减少手术时间及术中出血量,延长了生存时间。结论胃癌伴呕血术前化疗栓塞,创伤轻微,疗效显著,应作为术前的一项常规治疗手段。
Objective To investigate the efficacy of preoperative chemoembolization and adverse reactions in gastric cancer with hematemesis and the effect on surgical resection rate. Methods 65 cases of gastric cancer with hematemesis, divided into chemotherapy and surgery group and surgery group. Thirty patients underwent chemoembolization surgery were enrolled in this study. The size, shape, degree of tumor necrosis and adverse reactions after chemoembolization were measured. Surgical resection was performed 7 to 15 days later. The operation time, intraoperative blood loss, surgical resection rate and survival time , And compared with the simple operation group of 35 cases. Results ① Chemoembolization can vomit blood disappeared, the tumor has a certain degree of necrosis, and the lesion has been reduced, minor adverse reactions. ② Chemoembolization and then surgical resection, not only can improve the surgical resection rate, but also reduce the operation time and intraoperative blood loss, prolonging the survival time. Conclusion Gastric cancer with hematemesis before chemotherapy and embolization, minor trauma, significant effect, should be used as a routine preoperative treatment.