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目的探讨甲亢合并糖尿病的临床治疗方式和效果。方法 51例经临床确诊为甲亢合并糖尿病患者,在治疗过程中使用甲疏咪唑联合瑞格列奈和胰岛素注射的方式,分别记录治疗前后患者血糖和甲状腺指标变化。结果 1 51例患者甲状腺功能:治疗后血清游离三碘甲状腺原氨酸水平(4.48±0.87)ng/L明显低于治疗前(14.49±7.28)ng/L,差异具有统计学意义(P<0.05);治疗后血清游离甲状腺激素水平(7.48±1.19)ng/L明显低于治疗前(49.37±13.48)ng/L,差异具有统计学意义(P<0.05);治疗后促甲状腺激素水平(3.87±0.52)m U/L明显高于治疗前(0.03±0.01)m U/L,差异具有统计学意义(P<0.05)。2 51例患者血糖:治疗后空腹血糖值(6.28±0.81)mmol/L明显低于治疗前(12.47±2.19)mmol/L,差异具有统计学意义(P<0.05);治疗后餐后2 h血糖值(7.28±1.83)mmol/L明显低于治疗前(18.96±4.33)mmol/L,差异具有统计学意义(P<0.05)。结论治疗甲亢合并糖尿病时必须对两种疾病均开展治疗,调整血糖和甲状腺功能指标,从而保证治疗效果。
Objective To investigate the clinical treatment and effect of hyperthyroidism complicated with diabetes. Methods 51 cases of clinically diagnosed hyperthyroidism with diabetes mellitus were treated with methimazole combined with repaglinide and insulin injections. The changes of blood glucose and thyroid indexes were recorded before and after treatment. Results Thyroid function in 51 patients was significantly lower than that before treatment (4.48 ± 0.87) ng / L after treatment (4.48 ± 0.87) ng / L, the difference was statistically significant (P <0.05 ). After treatment, serum free thyroid hormone level (7.48 ± 1.19) ng / L was significantly lower than that before treatment (49.37 ± 13.48) ng / L, with statistical significance (P 0. 05); thyrotropin level ± 0.52) m U / L was significantly higher than that before treatment (0.03 ± 0.01) m U / L, the difference was statistically significant (P <0.05). The blood sugar of 51 patients was significantly lower than that before treatment (6.28 ± 0.81) mmol / L (12.47 ± 2.19) mmol / L, the difference was statistically significant (P <0.05) Blood glucose (7.28 ± 1.83) mmol / L was significantly lower than that before treatment (18.96 ± 4.33) mmol / L, the difference was statistically significant (P <0.05). Conclusion Treatment of hyperthyroidism with diabetes must be treated for both diseases, adjusting blood glucose and thyroid function indicators, thus ensuring the treatment effect.