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目的探讨前列腺癌根治术后Gleason评分升级的相关危险因素。方法回顾性分析2014年8月至2016年9月175例行前列腺癌根治术患者的年龄、前列腺特异性抗原PSA、前列腺体积、穿刺阳性针数和穿刺癌组织最大占比等指标,统计穿刺与根治术后Gleason评分差异,并应用Logistic回归分析前列腺癌根治术后Gleason评分升级的危险因素。结果 175例患者中,44例(25.1%)出现术后病理Gleason评分较穿刺前升高。前列腺体积是前列腺癌根治术后Gleason评分升级的独立预测因素。结论前列腺体积较小的前列腺癌患者,术后Gleason评分发生升级的可能性较大。
Objective To investigate the risk factors associated with the Gleason score after radical prostatectomy. Methods The clinical data of 175 patients with prostate cancer underwent radical prostatectomy from August 2014 to September 2016 were retrospectively analyzed in terms of age, prostate-specific antigen (PSA), volume of prostate, number of needles punctured and the maximum proportion of puncture cancer. Gleason score after radical operation was significantly different, and Logistic regression was used to analyze the risk factors of Gleason score upgrade after radical prostatectomy. Results Of the 175 patients, 44 patients (25.1%) had postoperative pathological Gleason score higher than that before puncture. Prostate volume is an independent predictor of Gleason score escalation after radical prostatectomy. Conclusion Prostate cancer patients with smaller prostate volume are likely to have an elevated Gleason score.