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目的 :探讨心肌挫伤 (MC)后右心室功能的变化规律。方法 :采用单光子发射计算机断层照相机(SPECT)检测中度至重度 MC模型兔右心室功能。结果 :右心室射血分数 (EF)、1/ 3射血分数 (1/ 3 EF)、1/ 3射血率 (1/ 3 ER)在伤后 2 4小时〔分别为 0 .2 9± 0 .0 4、0 .2 7± 0 .12和 (53 7± 12 3 )× 10 - 2 / s〕仍然明显低于伤前〔分别为 0 .3 9± 0 .0 7、0 .3 7± 0 .10和 (788± 175)× 10 - 2 / s〕,P<0 .0 5;高峰充盈率 (PFR)在伤后 2小时下降明显〔(12 54± 188)× 10 - 2 / s比 (1874± 62 4 )× 10 - 2 / s,P<0 .0 5〕,然后开始上升 ,2 4小时为 (2 0 14± 787)× 10 - 2 / s,与伤前比较差异不显著 (P>0 .0 5) ;1/ 3充盈分数 (1/ 3 FF)在伤后 0 .5小时下降明显 (0 .4 4± 0 .16比 0 .2 6±0 .0 7,P<0 .0 5) ,而 1/ 3充盈率 (1/ 3 FR)上升明显〔(974± 4 0 2 )× 10 - 2 / s比 (12 4 7± 886)× 10 - 2 / s,P<0 .0 5〕,伤后 2小时又明显下降 ,8小时恢复〔分别为 0 .50± 0 .0 3和 (860± 168)× 10 - 2 / s〕,P均 >0 .0 5;PFR/ PER、1/ 3 FR与 1/ 3 ER比值在伤后 0 .5小时即开始下降 (分别为 0 .91± 0 .4 3和 0 .82± 0 .65,P<0 .0 5) ,PFR/ PER在伤后 2 4小时 (0 .98± 0 .50 )恢复至伤前水平 ,1/ 3
Objective: To investigate the changes of right ventricular function after myocardial contusion (MC). Methods: The right ventricular function in moderate to severe MC model rabbits was detected by single photon emission computed tomography (SPECT). RESULTS: Right ventricular ejection fraction (EF), 1/3 ejection fraction (1/3 EF) and 1/3 ejection rate (1/3 ER) were significantly higher at 24h after injury 0 .0 4,0. 2 7 ± 0,12 and (53 7 ± 12 3) × 10 -2 / s] were still significantly lower than pre-injury 〔0.39 ± 0.07,0.3 7 ± 0. 10 and (788 ± 175) × 10 - 2 / s], P <0. 05, respectively. Peak perfused rate (PFR) decreased significantly at 2 hours post injury (12 54 ± 188) × 10 -2 / s ratio (1874 ± 62 4) × 10-2 / s, P <0.05), and then began to rise, 2 4 hours (2 0 14 ± 787) × 10 -2 / s, compared with pre-injury (P> 0.05). The 1/3 filling fraction (1/3 FF) decreased significantly at 0 .5 hours after injury (0.44 ± 0.16 vs. 0.26 ± 0. 0 7, P <0.05), while the 1/3 filling rate (1/3 FR) increased significantly (974 ± 4 0 2) × 10 -2 / s vs (12 4 7 ± 886) × 10 -2 / s, P <0.05), and significantly decreased at 2 hours after injury and recovered at 8 hours (0 .50 ± 0. 03 and (860 ± 168) × 10 - 2 / s, respectively) 0 .0 5; The ratio of PFR / PER, 1/3 FR and 1/3 ER decreased at 0 .5 hours after injury (0 .91 ± 0 .4 3 and 0 .82 ± 0 .65 respectively, P <0. 05), PFR / PER after injury 2 4 hours (0 .98 ± 0 .50) returned to pre-injury level, 1/3