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目的总结并探讨近10年来天津市儿童医院PICU危重症患儿的死亡原因变化情况和死亡相关因素的特点。方法对1995-07—2005-07于天津市儿童医院PICU病房死亡的119例患儿资料进行回顾,运用统计学方法进行Ridit分析,u检验,χ2检验。结果对不同年龄段死亡患儿的性别采用Ridit分析,经u检验,提示死亡患儿不同年龄段的性别构成差异有统计学意义(P<0.01)。将1995—2000、2000—2005的死亡患儿按病因分为感染因素、非感染因素与未明诊断3组,经χ2检验,提示PICU近5年死亡患儿的疾病病因与既往5年差异有统计学意义(P<0.05)。将10年间每个年龄段的死亡患儿病因细分为感染因素、非感染因素、未明诊断3种,经χ2检验,提示PICU死亡患儿不同年龄组的疾病病因差异有显著性意义(P<0.05)。结论近10年来,天津市儿童医院PICU的死亡疾病构成及死亡原因发生了较为显著的变化,感染性疾病的发生相对减少,非感染性疾病的比率相对增高。1个月至1岁的婴儿患者以及农村患儿的病死率相对较高,且以感染性因素为主。意外伤害造成的死亡相对集中于1～4岁年龄组,且高发于农村。
Objective To summarize and discuss the causes of mortality and related factors of death in children with critical illness in PICU in Tianjin Children’s Hospital in the past 10 years. Methods The data of 119 children who died in PICU from the Children’s Hospital of Tianjin Hospital from July 2006 to July 2005 were reviewed. Ridit analysis, u-test and χ2 test were performed by statistical methods. RESULTS: Ridit analysis was used to analyze the gender of children who died in different age groups. The u test showed that there was a statistically significant difference in the gender composition of children with different ages (P<0.01). The deaths of children from 1995 to 2000 and 2000 to 2005 were divided into three groups according to their etiology: infectious factors, non-infectious factors, and undiagnosed diseases. After the χ2 test, the causes of the deaths of PICU in the past 5 years were statistically different from those in the previous 5 years. Significance (P<0.05). The causes of death in each age group in 10 years were subdivided into infection factors, non-infective factors, and undetermined diagnosis. After the χ2 test, it was suggested that the disease causes of PICU death in different age groups had significant differences (P< 0.05). Conclusion In the past 10 years, the composition of deaths and causes of death of PICU in Tianjin Children’s Hospital have changed significantly. The incidence of infectious diseases has been relatively reduced, and the rate of non-infectious diseases has been relatively high. The mortality rate of infants from 1 month to 1 year old and rural children is relatively high, and is mainly caused by infectious factors. Death caused by accidental injuries is relatively concentrated in the 1 to 4-year-old age group, and it is high in rural areas.