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为了获得激光焊接工艺参数对离体生物组织融合效果的影响规律,设计实验探究了激光功率、激光扫描方式等参数对离体皮肤切口融合形貌及抗张强度的影响,并对工艺参数进行了优化。结果表明,采用小功率长时间工艺规范焊接离体皮肤组织,组织切口融合效果较好、抗张强度较高,并且可以减小不可逆的热损伤;采用分段扫描焊接方式,可以加强切口附近成分的活性,减小切口热损伤。在此基础上,采用优化的工艺参数进行可靠性实验,并对切口抗张强度进行了测试。结果表明,在该工艺条件下,组织切口可实现全层融合,并且无烧损、碳化等缺陷,与连续激光焊接工艺相比,焊接时间可减少30%~40%,焊后组织切口抗张强度可达0.38 MPa,满足强度要求。
In order to obtain the influence rule of laser welding process parameters on the fusion effect of ex vivo biological tissue, the effects of laser power, laser scanning mode and other parameters on the fusion morphology and tensile strength of incisional skin incision were studied, and the process parameters optimization. The results show that welding the exfoliated skin tissue with low-power and long-time process standard has good effect of tissue incision fusion, high tensile strength and less irreversible heat damage. By using the sectional scanning welding method, the components near the incision can be strengthened Activity, reduce the thermal incision injury. On the basis of this, the reliability experiment was carried out with the optimized process parameters, and the tensile strength of the notch was tested. The results show that under this condition, the tissue incision can achieve full-thickness fusion with no defects such as burning and carbonization. Compared with the continuous laser welding process, the welding time can be reduced by 30% ~ 40% Strength up to 0.38 MPa, to meet the strength requirements.