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目的 :了解年轻患者膀胱移行细胞癌的自然史及预后。方法 :回顾了 5 3例有记录的 4 0岁以下 (包括 4 0岁 )的膀胱移行细胞癌病例 ,平均随访 6 8个月 ,中位随访 5 6个月。结果 :5 3例病人中 4 0例表现为浅表性膀胱癌 ,13例有肌层浸润。其 3,5 ,10年的复发率分别为 2 0 .89% ,32 .16 % ,5 5 .0 1% ;3,5 ,10年的进展率分别为13.5 1% ,18.92 % ,35 .5 8% ;3,5 ,10年的生存率分别为 91.95 % ,85 .4 2 % ,74 .5 8%。结论 :年轻患者的膀胱移行癌具有相对良性的预后 ,但其治疗应同一般膀胱移行细胞癌患者一样 ,根据肿瘤的分期及分级来决定。
Objective: To understand the natural history and prognosis of bladder transitional cell carcinoma in young patients. Methods: Fifty-three cases of bladder transitional cell carcinoma under 40 years of age (including 40 years) were reviewed. The average follow-up was 68 months. The median follow-up was 56 months. Results: 40 of 53 patients showed superficial bladder cancer and 13 had myometrial invasion. The recurrence rates in 3,5 and 10 years were 20.89%, 32.16% and 55.01%, respectively. The rates of progression in 3,5 and 10 years were 13.51% and 18.92%, respectively. The survival rates in 3,5 and 10 years were 91.95%, 85.42% and 74.58% respectively. Conclusion: The younger patients with bladder transitional carcinoma have a relatively benign prognosis, but the treatment should be the same with the general bladder transitional cell carcinoma patients, according to the tumor stage and grade to decide.