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目的:研究地佐辛与瑞芬太尼用于经腹直肠癌根治手术中麻醉镇痛中的效果差异。方法:在我院肿瘤外科收治的直肠癌患者中随机选出120例作为观察对象,全部患者均在我院接受经腹直肠癌根治术治疗,根据其术中的麻醉镇痛方法分成观察组和对照组,其中对照组患者采用瑞芬太尼维持麻醉镇痛,观察组患者采表1两组患者的肝肾功能指标值对比组别用地佐辛维持麻醉镇痛,对比分析两组患者的MAP、心率、肝肾功能、苏醒时间、不良反应发生率等指标。结果:两组患者手术后拔管时,观察组患者的MAP和HR值均明显低于对照组(P<0.05);观察组患者的苏醒时间比对照组明显缩短,且在术后48h内,观察组患者的不良反应发生率显著低于对照组(P<0.05)。结论:在经腹直肠癌根治术的术中麻醉镇痛中,与瑞芬太尼相比,地佐辛的安全性更高,且患者苏醒快,对肝肾功能、呼吸系统等的影响不大,值得推广应用。
Objective: To study the effect of dezocine and remifentanil on anesthesia analgesia in radical surgery of transabdominal rectal cancer. Methods: Totally 120 patients with rectal cancer admitted to our hospital were selected as observational subjects. All patients underwent radical resection of abdominal rectal cancer in our hospital. According to the method of anesthesia and analgesia during operation, they were divided into observation group and control group. Control group, in which the control group of patients with remifentanil to maintain narcotic analgesia, the observation group of patients taking Table 1 two groups of patients with liver and kidney function index values compared with the group Zuozuo to maintain anesthesia analgesia, comparative analysis of two groups of patients with MAP , Heart rate, liver and kidney function, recovery time, the incidence of adverse reactions and other indicators. Results: After extubation, MAP and HR in observation group were significantly lower than those in control group (P <0.05); recovery time in observation group was significantly shorter than control group, and within 48 hours after operation, The incidence of adverse reactions in observation group was significantly lower than that in control group (P <0.05). CONCLUSIONS: Dezocine is more safe than remifentanil in intraoperative anesthesia and analgesia for radical resection of rectal cancer, and patients are more rapidly awake and have less effect on liver and renal function, respiratory system, etc. Large, worth promoting application.