论文部分内容阅读
呋喃丹,又名虫螨威,卡巴呋喃,曲锐特.属氨基甲酸酯类化合物,无臭无味、无腐蚀性,难溶于水.在中性和微酸性溶液中稳定,在硷性和强酸性溶液中易水解。是我国近年来开始应用的新型广谱杀虫剂.中毒机理呋喃丹侵入机体后,主要毒理作用为抑制乙酰胆硷酯酶,胆硷酯酶活性中心丝氨酸上的羟基被氨基甲酰化,从而失去对乙酰胆硷的酶解能力.但由于氨基甲酸酯类农药和胆硷酯酶的结合属可逆性,所以在机体内的水解代谢较快,半衰期较短(6~12小时).—般约4小时左右胆硷酯酶活力即开始恢复,24小时几乎完全恢复正常.中毒途径呋喃丹的中毒方式和有机
Carbofuran, also known as carbofuran, carbofuran, Qu Rui special. Is a carbamate compound, odorless, non-corrosive, insoluble in water. In neutral and slightly acidic solution, stable, alkaline and Strong acid solution easy to hydrolysis. Is a new type of broad-spectrum insecticide which has been applied in recent years in our country. The toxic mechanism of carbofuran invades the body, the main toxicological effect is to inhibit the acetylcholine esterase, the hydroxy group of serine in the active center of cholinesterase is carbamoylated, Thus losing the ability of enzymatic hydrolysis of acetylcholine.However, due to the reversibility of the combination of carbamates and cholinesterase, the hydrolysis and metabolism in the body is faster and the half-life is shorter (6-12 hours) .- About 4 hours or so cholinesterase activity began to recover, almost completely restored to normal within 24 hours. Poisoning way Carbofuran poisoning and organic