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应用图象分析技术对３６例吸烟肺标本的肺泡接触、小气道炎症和其相连肺泡壁段上细胞构成（ＣｅｌＬｓ／ｍｍ）进行计量学测量。吸烟肺分为无肺气肿组（ＮＥ），小叶中央型（ＣＬＥ）和全小叶型肺气肿组（ＰＬＥ）。结果：肺泡接触参数中，ＣＬＥ相邻两个正常肺泡接触之间的距离（Ｄｉｓｔａｎｃｅ）和异常肺泡接触百分数（％Ａｂｎｏｒｍａｌ）均显著高于ＮＥ（Ｐ＜０．０１），ＰＬＥ和ＮＥ间无明显区别；并且Ｄｉｓｔａｎｃｅ和％Ａｂｎｏｒｍａｌ分别与小气道炎症（ＩＮＥ）和Ｃｅｌｌｓ／ｍｍ显著相关，然而这种关系仅见于ＣＬＥ。吸烟者肺泡接触的破坏与小气道炎症有密切关系。
The image analysis technique was used to measure the alveolar contact, the airway inflammation, and the cell composition (CelLs / mm) of the connected alveolar wall in 36 smoking lung specimens. Smoking lungs were divided into no emphysema group (NE), central lobular (CLE) and total lobular emphysema group (PLE). RESULTS: In the alveolar contact parameters, the distance between CLE adjacent normal alveolar contacts and the percentage of abnormal alveolar contact (% Abnormal) were significantly higher than that of NE (P <0.01), and there was no significant difference between PLE and NE ; And Distance and% Abnormal were significantly associated with small airway inflammation (INE) and Cells / mm, respectively, however this relationship was only seen in CLE. Smoker alveolar contact damage and small airway inflammation are closely related.