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目的探讨超高频电波刀(LEEP)手术治疗宫颈癌前病变(CIN)的临床治疗效果。方法回顾性分析行LEEP术治疗的72例CIN患者的临床资料,并分析患者的手术治疗情况,将术前宫颈活检结果与术后病理检查结果进行对比。结果本组72例患者手术时间为3~16 min,平均手术时间为(7.02±3.39)min,术中出血量为1~45 ml,平均出血量(20.03±8.58)ml。67例(93.06%)患者术后病理检查结果与术前活检结果一致,3例(4.17%)术后病理级别上升,再次行LEEP手术后病理检查结果与术前检查一致,2例(2.78%)术后病理检查结果下降。术中患者无明显并发症,仅1例术后出现阴道流血,采取电凝止血后痊愈。在1~2年的随访中无一例患者病情复发。结论 LEEP手术治疗CIN安全有效,具有操作简单、手术时间短、术中出血量少等显著优点,值得临床推广。
Objective To investigate the clinical effect of ultra-high frequency electric wave knife (LEEP) in the treatment of cervical precancerous lesions (CIN). Methods The clinical data of 72 CIN patients treated by LEEP were retrospectively analyzed. The surgical treatment of the patients was analyzed. The results of preoperative cervical biopsy and postoperative pathological examination were compared. Results The operation time of 72 patients in this study ranged from 3 to 16 minutes. The average operation time was (7.02 ± 3.39) min. The intraoperative blood loss was 1 ~ 45 ml and the average amount of bleeding was (20.03 ± 8.58) ml. The postoperative pathological findings of 67 patients (93.06%) were consistent with the results of preoperative biopsy, and the pathological grade of 3 patients (4.17%) was increased after operation. The pathological results of LEEP after reoperation were consistent with those of preoperative examination. Postoperative pathological examination results decreased. No intraoperative complications, only 1 case of postoperative vaginal bleeding, coagulation after hemostasis. None of the patients had a relapse during a follow-up of 1 to 2 years. Conclusions The LEEP surgical treatment of CIN safe and effective, with simple operation, short operative time, less blood loss and other significant advantages, is worth clinical promotion.