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目的 探讨胎盘组织中血管紧张素 与妊娠高血压综合征 (妊高征 )发病的关系。方法 用放射免疫法测定妊高征大鼠 (15只 )及正常妊娠大鼠 (5只 )胎盘组织中血管紧张素 水平。结果 妊高征大鼠胎盘组织中血管紧张素 水平〔(2 5 1± 38) pg/ mg〕较正常妊娠大鼠〔(132± 30 ) pg/ m g〕明显增高 (P<0 .0 0 1)。结论 胎盘组织血管紧张素 可能参与了妊高征的发生和发展
Objective To investigate the relationship between angiotensin and pregnancy induced hypertension (PIH) in placenta. Methods The levels of angiotensin in placenta of pregnant rats with PIH (15) and normal pregnant rats (5) were determined by radioimmunoassay. Results Compared with normal pregnant rats, the level of angiotensin (P <0.05) in placental tissue of PIH rats was significantly higher than that of normal pregnant rats 〔(52 ± 38) pg / mg〕 ). Conclusion Placenta angiotensin may be involved in the occurrence and development of PIH