蜘蛛毒素含有多种化学成分,除毒性作用外这些物质对机体产生多重影响并具有多种活性。近年来,大量新的毒性组分不断被分离纯化,其结构和功能性作用被广泛深入研究,蜘蛛毒素成为了生物毒素领域新的研究热点。本文对蜘蛛毒素在离子通道作用机制方面的最新研究进展进行了阐述,同时还探讨了蜘蛛毒素在医学实践中新的应用和发展。 Spider toxin contains a variety of chemical components, in addition to toxicity of these substances have multiple effects on the body and has a variety of activities. In recent years, a large number of new toxic components have been continuously isolated and purified, and their structural and functional roles have been extensively studied. The spider toxin has become a new research hotspot in the field of biological toxins. In this paper, the latest research progress on the mechanism of action of spider toxin in ion channel was expounded, and the new application and development of spider toxin in medical practice were also discussed.