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一般认为米托蒽醌是一种非发疱剂,在人体或试验动物静脉注射用药时都不会引起外渗型损伤或组织坏死.但已有静脉注射米托蒽醌后引起局部反应和组织坏死的报道.作者报道1例米托蒽醌静注引起组织损伤和坏死的严重不良反应.
It is generally believed that mitoxantrone is a non-blistering agent that does not cause extravasation or tissue necrosis when administered intravenously to humans or test animals, but has been reported to cause local reactions and tissue after intravenous administration of mitoxantrone Necrotic report. The authors reported a case of mitoxantrone intravenous injection of tissue damage and necrosis caused by serious adverse reactions.