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目的:评估阴性症状评估量表4条目（4-item Negative Symptom Assessment，NSA-4）中文版在精神分裂症患者中的信效度。方法:纳入172例精神分裂症患者进行NSA-4中文版及阴性症状评定量表（Scale for Assessment of Negative Symptoms， SANS）、PANSS、卡尔加里精神分裂症抑郁量表（Calgary Depression Scale for Schizophrenia， CDSS）评估。采用Cronbach α系数评价NSA-4中文版的内部一致性，采用组内相关系数（intraclass correlation coefficients， n ICC）评价评分者间一致性，以Spearman相关分析评价重测信度。采用Spearman相关分析，以NSA-4中文版与SANS的相关性评价其效标效度，与PANSS、CDSS的相关性评价其聚合效度和区分效度。n 结果:NSA-4中文版的Cronbach α系数为0.788，n ICC为0.661~0.958，重测信度n r=0.860。NSA-4中文版与SANS的相关系数为n r=0.801，与PANSS总分、PANSS阴性症状分及总体阴性症状评定的相关系数为n r=0.528~0.834，与PANSS阳性症状分、一般病理分、CDSS总分相关系数为n r=0.069~0.358。n 结论:NSA-4中文版具有良好的信效度，适用于精神分裂症患者阴性症状的临床快速评定。“,”Objectives:This study aims to evaluate the reliability and validity of the Chinese version of the 4-item Negative Symptom Assessment (NSA-4) in patients with schizophrenia.Methods:A total of 172 patients with schizophrenia were recruited and assessed with the Chinese version of NSA-4, the Scale for Assessment of Negative Symptoms (SANS), PANSS, and the Calgary Depression Scale for Schizophrenia (CDSS). Cronbach′s α was computed to evaluate internal consistency. Intraclass correlation coefficients (ICCs) were computed to evaluate the inter-rater reliability and Spearman's correlation analysis was used to evaluate the test-retest reliability. Spearman′s correlation analyses were conducted between NSA-4 and SANS, PANSS, and CDSS to evaluate concurrent validity, convergent validity, and discriminant validity, respectively.Results:Cronbach′s α for the Chinese version of the NSA-4 was 0.788. ICCs were 0.661-0.958 and test-retest reliability was 0.860. The Chinese version of the NSA-4 showed satisfactory concurrent validity considering its high correlation with SANS (n r=0.801), excellent convergent validity considering its high correlation with PANSS total score and negative symptom subscale score (n r=0.528-0.834), and good discriminant validity considering its weak correlation with scores of the positive symptom subscale and general psychopathology subscale of PANSS and CDSS (n r=0.069-0.358).n Conclusion:The Chinese version of the NSA-4 has good psychometric properties. It is useful for rapid assessment of negative symptoms in patients with schizophrenia.