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目的探讨丙泊酚联合氯胺酮在小儿全身麻醉中的应用效果。方法全身麻醉手术的患儿100例随机分成观察组和对照组,每组50例,观察组采取丙泊酚联合氯胺酮,对照组采取氯胺酮,比较两组麻醉前后患儿的麻醉效果。结果两组患儿各时点平均动脉压(MAP)、心率(HR)比较差异均无统计学意义(P>0.05)。手术结束时观察组自主呼吸恢复时间、拔管时间明显少于对照组。观察组术后躁动、呛咳发生率显著低于对照组,差异有统计学意义(P<0.05)。结论丙泊酚联合氯胺酮在小儿麻醉中使用效果满意。
Objective To investigate the effect of propofol combined with ketamine in pediatric general anesthesia. Methods 100 cases of children under general anesthesia were randomly divided into observation group and control group, 50 cases in each group. Propofol and ketamine were used in the observation group. Ketamine was used in the control group. The anesthetic effect in both groups before and after anesthesia was compared. Results There was no significant difference in mean arterial pressure (MAP) and heart rate (HR) between two groups at each time point (P> 0.05). Observation group at the end of surgery spontaneous breathing recovery time, extubation time was significantly less than the control group. The incidence of postoperative agitation and cough in observation group was significantly lower than that in control group, the difference was statistically significant (P <0.05). Conclusion Propofol combined with ketamine in pediatric anesthesia with satisfactory results.