0 0 5 ) ;而F ERGa、b波振幅、峰潜时与对侧正常眼比较差别无统计学意义 (P >0 0 5 ) ;正常眼M ERG中心 1环的P1波振幅密度值最大、峰潜时最长。结论 :黄斑区病变可使M ERG中心 1环 (黄斑中心凹周围 0~ 5°区域 )的一阶kernel反应振幅降低、峰潜时缩短 ;短M序列记录时程短、采样少 ,可能更适合固视力差或检查欠合作者 ;M ERG通过不同的kernel反应可反映视网膜外层 (感光细胞层 )和内层 (神经节细胞等 )的功能 ,对评价后极部尤其是黄斑区视网膜功能有独特作用 ,其优越性大于全视野ERG。 Objective: To observe the retinal function with multifocal electroretinography (M ERG). Methods: 16 patients (16 eyes) confirmed by fundus fluorescein monocular macular lesions (middle, age-related macular degeneration, traumatic macular hemorrhage, etc.) were short binary M sequence recording multifocal electroretinography (RETIscan MultifocalERG , M ERG and GanzfeldF ERG according to ISCEV standard) were used to analyze the M ERG first order kernel reaction (FOK) and F ERG mixed maximal response (MCR) Features. Results: The amplitude of P1 wave amplitude in the central loop of M ERG in 16 cases with macular lesions was significantly lower than that in the contralateral (normal) eyes (P <0.01), and the peak latency was shorter (0 0 1
0.05). However, there was no significant difference in amplitudes and peak amplitudes of F ERGa and b wave between normal and contralateral eyes (P> 0.05). In the normal eye, the amplitude of P1 wave amplitude of ring 1 in the center of M ERG was the largest and the peak latency was the longest. CONCLUSIONS: Macular lesions can reduce the amplitude of first-order kernel reaction in the first ring of M ERG (0 ~ 5 ° around the fovea) and shorten the peak-to-peak latency. Short M sequences may record shorter duration and fewer samples and may be more suitable Poor visual acuity or check owe partner; M ERG through different Kernel reaction can reflect the outer layer of the retina (photoreceptor cell layer) and the inner layer (ganglion cells, etc.) function, the assessment of the Ministry of especially the macular retinal function Unique effect, its superiority than full-field ERG.