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目的探讨氟比洛芬酯超前镇痛对腹腔镜下子宫肌瘤剔除术患者拔管期应激反应的影响。方法 98例腹腔镜下子宫肌瘤剔除术患者,随机分为对照组和观察组,各49例。对照组:手术前无氟比洛芬酯超前镇痛;观察组:手术前给予患者氟比洛芬酯超前镇痛。观察并记录两组患者拔管即刻耐管情况和视觉模拟评分法(VAS)评分。结果观察组患者的耐管评分(0.9±0.3)分、疼痛VAS评分(1.4±0.3)分均低于对照组的(2.2±0.4)、(3.5±0.9)分,差异均有统计学意义(P<0.01)。结论麻醉诱导前给予氟比洛芬酯可部分抑制腹腔镜下子宫肌瘤剔除术导致的术后疼痛,有效的降低术后应激反应。
Objective To investigate the effect of flurbiprofen axetil preemptive analgesia on extubation stress response in laparoscopic myomectomy patients. Methods 98 cases of laparoscopic myomectomy patients were randomly divided into control group and observation group, 49 cases in each. Control group: Preoperative non-flurbiprofen axetil preemptive analgesia; observation group: Preoperative patients given flurbiprofen axetil preemptive analgesia. The immediate extubation and visual analogue scale (VAS) scores were observed and recorded in both groups. Results The tube resistance score (0.9 ± 0.3) and pain VAS score (1.4 ± 0.3) in the observation group were significantly lower than those in the control group (2.2 ± 0.4 and 3.5 ± 0.9), respectively P <0.01). Conclusion The administration of flurbiprofen axetil before induction of anesthesia can partially inhibit the postoperative pain caused by laparoscopic myomectomy and effectively reduce postoperative stress response.