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目的探讨胸水CEA、ADA、LDH的检测对结核性和恶性胸腔积液鉴别诊断的价值。方法收集来我院住院确诊的结核性胸腔积液33例和恶性胸腔积液28例及61例漏出性胸腔积液进行CEA、ADA和LDH检测,并进行统计学分析。结果恶性胸腔积液CEA的含量明显高于结核性和漏出性胸腔积液(P<0.05)有显著差异,结核性胸水的ADA含量均明显高于漏出性胸水组和恶性胸水组(P<0.05)有显著差异,恶性胸腔积液的LDH含量明显高于漏出性胸水和结核性胸腔积液(P<0.05)有显著差异。结论检测CEA、ADA、LDH可作为结核性、恶性胸腔积液的鉴别诊断提供较好的参考依据,且简单、安全,值得基层医院推广。
Objective To investigate the diagnostic value of pleural effusion CEA, ADA and LDH in the differential diagnosis of tuberculous and malignant pleural effusion. Methods Thirty-three cases of tuberculous pleural effusion diagnosed in our hospital and 28 cases of malignant pleural effusion and 61 cases of leakage pleural effusion were collected for CEA, ADA and LDH detection and statistical analysis. Results The content of CEA in malignant pleural effusion was significantly higher than that in tuberculous and leaky pleural effusion (P <0.05). The ADA content in tuberculous pleural effusion was significantly higher than that in the esophageal effusion and malignant pleural effusion group (P <0.05 ), The LDH content of malignant pleural effusion was significantly higher than that of effusion pleural effusion and tuberculous pleural effusion (P <0.05). Conclusion The detection of CEA, ADA, LDH can be used as a good reference for the differential diagnosis of tuberculous and malignant pleural effusion. It is simple and safe and worth to be popularized in primary hospitals.