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目的:观察川芎茶调散治疗过敏性结膜炎患者的临床疗效及其安全性。方法:将收治的138例患者按照随机数字表法分为2组各69例。对照组予0.1%盐酸奥洛他定滴眼液。观察组在对照组治疗方案的基础上加用川芎茶调散治疗。2组疗程均为14天。比较2组临床疗效,治疗前后主要症状、体征评分变化,及安全性评价。结果:2组临床疗效比较,总有效率观察组92.75%,对照组76.81%,2组临床疗效比较,差异有统计学意义(P<0.05)。治疗后,2组患者眼痒、流泪、眼异物感评分降低,分别与治疗前比较,差异均有统计学意义(P<0.05);治疗后,观察组患者眼痒、流泪、眼异物感评分均低于对照组,2组间比较,差异均有统计学意义(P<0.05)。治疗后,2组患者上睑结膜乳头、下睑结膜乳头、分泌物评分均降低,差异均有统计学意义(P<0.05);治疗后,观察组患者上睑结膜乳头、下睑结膜乳头、分泌物评分均低于对照组,2组间比较,差异均有统计学意义(P<0.05)。2组用药期间均未出现严重不良反应。结论:川芎茶调散治疗过敏性结膜炎患者临床疗效良好,且用药安全性良好。
Objective: To observe the curative effect and safety of chuanxiongcha tea in treating patients with allergic conjunctivitis. Methods: 138 patients admitted to the random number table divided into two groups of 69 cases. The control group was given 0.1% olopatadine hydrochloride eye drops. Observation group in the control group based on the treatment program with Chuanxiongcha tune transfer treatment. The two groups were treated for 14 days. The clinical efficacy, the main symptoms before and after treatment, the changes of the signs and scores, and the safety evaluation were compared between the two groups. Results: Compared with the two groups, the total effective rate was 92.75% in the observation group and 76.81% in the control group. There was significant difference in the clinical curative effect between the two groups (P <0.05). After treatment, the scores of itchy eyes, tearing eyes and foreign body sensation decreased in both groups, which were significantly different from those before treatment (P <0.05). After treatment, itchy eyes, tearing, Were lower than the control group, the difference between the two groups was statistically significant (P <0.05). After treatment, the scores of upper conjunctiva nipple, lower conjunctiva nipple, and secretions of the two groups were decreased after treatment, and the differences were statistically significant (P <0.05). After treatment, the patients in the observation group had a combination of upper conjunctiva nipple, lower conjunctiva nipple, Secretions were lower than the control group, between the two groups, the difference was statistically significant (P <0.05). No serious side effects occurred during the two groups. Conclusion: Chuanxiong tea tune scattered treatment of allergic conjunctivitis patients with good clinical efficacy, and medication safety is good.