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目的了解地方性砷中毒患者生存质量现况及病情严重程度对人生存质量的影响,为卫生行政部门制定相关防治决策提供依据。方法采用WHOQOL-BREF量表对山西省和内蒙古自治区砷中毒病人、病区对照和非病区对照人群进行访谈调查。运用卡方检验、方差分析等方法对比了各组人群的性别、文化程度构成情况和年龄等一般特征;采用以年龄为协变量的协方差分析对各组人群生存质量各个领域及自我评分进行比较分析。结果本次发放问卷379份,收到有效问卷331份,应答率87.34%;砷中毒轻、中、重组及内外对照组在文化程度、性别构成上差别无统计学意义(x2LR文=20.038,P=0.109;x2性别=3.419,P=0.636),年龄差别有统计学意义(F=3.773,P=0.002)。结论砷中毒严重程度对患者生理领域、心理领域、环境领域都有一定影响,尤其对中、重度砷中毒患者生存质量影响较大。
Objective To understand the impact of the quality of life and the quality of life on the quality of life of patients with endemic arsenism and to provide basis for the health administrative departments to make relevant prevention and control decisions. Methods The WHOQOL-BREF scale was used to investigate the arsenic poisoning patients, ward-controlled and non-ward-controlled people in Shanxi Province and Inner Mongolia Autonomous Region. The chi-square test and analysis of variance were used to compare the general characteristics such as gender, educational level and age of all groups. By using covariance analysis with age as a covariate, the quality of life of all groups was compared with each other analysis. Results A total of 379 questionnaires were sent out and 331 valid questionnaires were received, with a response rate of 87.34%. There was no significant difference in the educational level and gender of the mild, moderate, severe and arsenic poisoning groups (x2LR = 20.038, P = 0.109; x2 sex = 3.419, P = 0.636). The difference in age was statistically significant (F = 3.773, P = 0.002). Conclusion The severity of arsenic poisoning has certain influence on patients’ physiological, psychological and environmental fields, especially on the quality of life of moderate and severe arsenic poisoning patients.