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氦气可减轻心肌细胞和神经细胞缺血再灌注后的损伤[1-2],尽管氦气介导的细胞保护作用机制仍未阐明,但其部分信号传导通路已被证实。除通过不同的预处理和后处理方式发挥心、脑保护作用之外,氦气对肺、免疫系统及血管系统也有一定的保护作用[3-5]。氦气在人体内发挥了一定的生物学作用,但其确切作用机制尚需阐明。氦气有诸多特殊的理化性质,且并无血流动力学的副作用,这使其在危重患者中可能存
Helium can reduce the damage of myocardial cells and nerve cells after ischemia-reperfusion [1-2]. Although the mechanism of helium-mediated cytoprotection has not been elucidated yet, some signaling pathways have been confirmed. In addition to exerting cardiopulmonary and cerebral protective effects through different preconditioning and postconditioning methods, helium also has certain protective effects on the lungs, the immune system and the vascular system [3-5]. Helium in the human body has played a certain biological role, but its exact mechanism needs to be clarified. Helium has a number of special physicochemical properties with no haemodynamic side effects that make it potentially viable in critically ill patients