微核检测是反映染色体损伤程度的行之有效的方法,多用于人群监测指标和评价一些理化因子的遗传毒理效应,还可用于放射生物剂量计及肿瘤病人放射敏感性和辅助诊断及预后估计。目前,外周血淋巴细胞检测方法较多,其中以甲基纤维(M、C)法较好。甲基纤维素法制备微核标本,因受某些因素的影响,结果淋巴细胞核浆之间游离空隙较小,淋巴细胞体积略有缩小,经 Micronucleus detection is an effective method to reflect the extent of chromosome damage. It is mostly used in population monitoring indicators and to evaluate the genetic toxicological effects of some physical and chemical factors. It can also be used in radiological dosimeters and tumor patients for radiosensitivity and auxiliary diagnosis and prognosis estimation. . At present, there are many detection methods for peripheral blood lymphocytes, of which the methylcellulose (M, C) method is better. Methyl cellulose preparation of micronucleus specimens, due to certain factors, the results of lymphocyte nuclear plasma between the smaller free space, a slight reduction in lymphocyte volume, by